Does VINCRISTINE Cause Ototoxicity? 194 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 194 reports of Ototoxicity have been filed in association with VINCRISTINE (VinCRIStine Sulfate). This represents 0.3% of all adverse event reports for VINCRISTINE.
194
Reports of Ototoxicity with VINCRISTINE
0.3%
of all VINCRISTINE reports
2
Deaths
7
Hospitalizations
How Dangerous Is Ototoxicity From VINCRISTINE?
Of the 194 reports, 2 (1.0%) resulted in death, 7 (3.6%) required hospitalization, and 10 (5.2%) were considered life-threatening.
Is Ototoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VINCRISTINE. However, 194 reports have been filed with the FAERS database.
What Other Side Effects Does VINCRISTINE Cause?
Febrile neutropenia (8,676)
Off label use (6,562)
Disease progression (5,252)
Neutropenia (4,982)
Drug ineffective (4,084)
Pyrexia (3,460)
Product use in unapproved indication (3,073)
Thrombocytopenia (2,940)
Sepsis (2,791)
Anaemia (2,603)
What Other Drugs Cause Ototoxicity?
CISPLATIN (273)
CARBOPLATIN (208)
AMIKACIN (158)
ETOPOSIDE (121)
GENTAMICIN (108)
CYCLOSPORINE (105)
VANCOMYCIN (87)
LINEZOLID (82)
TOBRAMYCIN (78)
CYCLOPHOSPHAMIDE (76)
Which VINCRISTINE Alternatives Have Lower Ototoxicity Risk?
VINCRISTINE vs VINDESINE
VINCRISTINE vs VINORELBINE
VINCRISTINE vs VINORELBINE\VINORELBINE
VINCRISTINE vs VIREAD
VINCRISTINE vs VISIPAQUE