Does FLUOROURACIL Cause Cardiac failure? 428 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 428 reports of Cardiac failure have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 0.8% of all adverse event reports for FLUOROURACIL.
428
Reports of Cardiac failure with FLUOROURACIL
0.8%
of all FLUOROURACIL reports
80
Deaths
248
Hospitalizations
How Dangerous Is Cardiac failure From FLUOROURACIL?
Of the 428 reports, 80 (18.7%) resulted in death, 248 (57.9%) required hospitalization, and 62 (14.5%) were considered life-threatening.
Is Cardiac failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FLUOROURACIL. However, 428 reports have been filed with the FAERS database.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Neutropenia (4,400)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
What Other Drugs Cause Cardiac failure?
SACUBITRIL\VALSARTAN (4,504)
FUROSEMIDE (1,841)
APIXABAN (1,575)
CYCLOPHOSPHAMIDE (1,514)
DOXORUBICIN (1,367)
ADALIMUMAB (1,278)
DEXAMETHASONE (1,271)
TREPROSTINIL (1,168)
BISOPROLOL (1,159)
LENALIDOMIDE (1,115)
Which FLUOROURACIL Alternatives Have Lower Cardiac failure Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE