Does FLUOROURACIL Cause Gastric perforation? 44 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 44 reports of Gastric perforation have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 0.1% of all adverse event reports for FLUOROURACIL.
44
Reports of Gastric perforation with FLUOROURACIL
0.1%
of all FLUOROURACIL reports
14
Deaths
20
Hospitalizations
How Dangerous Is Gastric perforation From FLUOROURACIL?
Of the 44 reports, 14 (31.8%) resulted in death, 20 (45.5%) required hospitalization, and 6 (13.6%) were considered life-threatening.
Is Gastric perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FLUOROURACIL. However, 44 reports have been filed with the FAERS database.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Neutropenia (4,400)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
What Other Drugs Cause Gastric perforation?
IBUPROFEN (113)
BEVACIZUMAB (110)
ADALIMUMAB (97)
CARBIDOPA\LEVODOPA (81)
PREDNISONE (70)
CISPLATIN (68)
OXALIPLATIN (68)
DEXAMETHASONE (66)
CAPECITABINE (64)
RITUXIMAB (59)
Which FLUOROURACIL Alternatives Have Lower Gastric perforation Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE