Does FLUOROURACIL Cause Hyperleukocytosis? 17 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 17 reports of Hyperleukocytosis have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 0.0% of all adverse event reports for FLUOROURACIL.
17
Reports of Hyperleukocytosis with FLUOROURACIL
0.0%
of all FLUOROURACIL reports
9
Deaths
12
Hospitalizations
How Dangerous Is Hyperleukocytosis From FLUOROURACIL?
Of the 17 reports, 9 (52.9%) resulted in death, 12 (70.6%) required hospitalization, and 9 (52.9%) were considered life-threatening.
Is Hyperleukocytosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FLUOROURACIL. However, 17 reports have been filed with the FAERS database.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Neutropenia (4,400)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
What Other Drugs Cause Hyperleukocytosis?
CYCLOPHOSPHAMIDE (55)
PREDNISONE (54)
TRETINOIN (52)
ARSENIC TRIOXIDE (49)
RITUXIMAB (49)
ACETAMINOPHEN (44)
VINCRISTINE (44)
DEXAMETHASONE (42)
PANTOPRAZOLE (38)
AMOXICILLIN (36)
Which FLUOROURACIL Alternatives Have Lower Hyperleukocytosis Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE