Does FLUOROURACIL Cause Lactic acidosis? 97 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 97 reports of Lactic acidosis have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 0.2% of all adverse event reports for FLUOROURACIL.
97
Reports of Lactic acidosis with FLUOROURACIL
0.2%
of all FLUOROURACIL reports
19
Deaths
66
Hospitalizations
How Dangerous Is Lactic acidosis From FLUOROURACIL?
Of the 97 reports, 19 (19.6%) resulted in death, 66 (68.0%) required hospitalization, and 20 (20.6%) were considered life-threatening.
Is Lactic acidosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FLUOROURACIL. However, 97 reports have been filed with the FAERS database.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Neutropenia (4,400)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
What Other Drugs Cause Lactic acidosis?
METFORMIN (16,316)
AMLODIPINE (886)
LINEZOLID (824)
FUROSEMIDE (698)
ACETAMINOPHEN (561)
METFORMIN\SITAGLIPTIN (557)
ALBUTEROL (467)
EMPAGLIFLOZIN (434)
RAMIPRIL (430)
BISOPROLOL (425)
Which FLUOROURACIL Alternatives Have Lower Lactic acidosis Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE