Does FLUOROURACIL Cause Pancytopenia? 562 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 562 reports of Pancytopenia have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 1.1% of all adverse event reports for FLUOROURACIL.
562
Reports of Pancytopenia with FLUOROURACIL
1.1%
of all FLUOROURACIL reports
130
Deaths
350
Hospitalizations
How Dangerous Is Pancytopenia From FLUOROURACIL?
Of the 562 reports, 130 (23.1%) resulted in death, 350 (62.3%) required hospitalization, and 71 (12.6%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
Yes, Pancytopenia is listed as a known adverse reaction in the official FDA drug label for FLUOROURACIL.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Neutropenia (4,400)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which FLUOROURACIL Alternatives Have Lower Pancytopenia Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE