Does FLUOROURACIL Cause Proctalgia? 90 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 90 reports of Proctalgia have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 0.2% of all adverse event reports for FLUOROURACIL.
90
Reports of Proctalgia with FLUOROURACIL
0.2%
of all FLUOROURACIL reports
14
Deaths
52
Hospitalizations
How Dangerous Is Proctalgia From FLUOROURACIL?
Of the 90 reports, 14 (15.6%) resulted in death, 52 (57.8%) required hospitalization, and 2 (2.2%) were considered life-threatening.
Is Proctalgia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FLUOROURACIL. However, 90 reports have been filed with the FAERS database.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Neutropenia (4,400)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
What Other Drugs Cause Proctalgia?
ADALIMUMAB (532)
VEDOLIZUMAB (321)
INFLIXIMAB (250)
INFLIXIMAB-DYYB (156)
METHOTREXATE (152)
RIBAVIRIN (134)
CYCLOPHOSPHAMIDE (116)
PREDNISONE (116)
CAPECITABINE (107)
BEVACIZUMAB (96)
Which FLUOROURACIL Alternatives Have Lower Proctalgia Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE