Does METHOTREXATE Cause Proctalgia? 152 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 152 reports of Proctalgia have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
152
Reports of Proctalgia with METHOTREXATE
0.1%
of all METHOTREXATE reports
2
Deaths
87
Hospitalizations
How Dangerous Is Proctalgia From METHOTREXATE?
Of the 152 reports, 2 (1.3%) resulted in death, 87 (57.2%) required hospitalization, and 25 (16.4%) were considered life-threatening.
Is Proctalgia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 152 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Proctalgia?
ADALIMUMAB (532)
VEDOLIZUMAB (321)
INFLIXIMAB (250)
INFLIXIMAB-DYYB (156)
RIBAVIRIN (134)
CYCLOPHOSPHAMIDE (116)
PREDNISONE (116)
CAPECITABINE (107)
BEVACIZUMAB (96)
TELAPREVIR (94)
Which METHOTREXATE Alternatives Have Lower Proctalgia Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA