Does FLUOROURACIL Cause Second primary malignancy? 212 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 212 reports of Second primary malignancy have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 0.4% of all adverse event reports for FLUOROURACIL.
212
Reports of Second primary malignancy with FLUOROURACIL
0.4%
of all FLUOROURACIL reports
55
Deaths
58
Hospitalizations
How Dangerous Is Second primary malignancy From FLUOROURACIL?
Of the 212 reports, 55 (25.9%) resulted in death, 58 (27.4%) required hospitalization, and 16 (7.5%) were considered life-threatening.
Is Second primary malignancy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FLUOROURACIL. However, 212 reports have been filed with the FAERS database.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Neutropenia (4,400)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
What Other Drugs Cause Second primary malignancy?
CYCLOPHOSPHAMIDE (1,247)
DOXORUBICIN (1,151)
VINCRISTINE (908)
IMATINIB (763)
PALBOCICLIB (658)
RITUXIMAB (646)
RUXOLITINIB (611)
ETOPOSIDE (573)
PREDNISONE (517)
OCTREOTIDE (496)
Which FLUOROURACIL Alternatives Have Lower Second primary malignancy Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE