Does FLUOROURACIL Cause Systemic scleroderma? 34 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 34 reports of Systemic scleroderma have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 0.1% of all adverse event reports for FLUOROURACIL.
34
Reports of Systemic scleroderma with FLUOROURACIL
0.1%
of all FLUOROURACIL reports
0
Deaths
10
Hospitalizations
How Dangerous Is Systemic scleroderma From FLUOROURACIL?
Of the 34 reports, 10 (29.4%) required hospitalization, and 14 (41.2%) were considered life-threatening.
Is Systemic scleroderma Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FLUOROURACIL. However, 34 reports have been filed with the FAERS database.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Neutropenia (4,400)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
What Other Drugs Cause Systemic scleroderma?
RITUXIMAB (54)
CYCLOPHOSPHAMIDE (53)
MACITENTAN (52)
DOCETAXEL (49)
METHOTREXATE (45)
MYCOPHENOLATE MOFETIL (44)
SELEXIPAG (34)
TREPROSTINIL (34)
BOSENTAN (30)
NINTEDANIB (29)
Which FLUOROURACIL Alternatives Have Lower Systemic scleroderma Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE