Does FLUOROURACIL Cause Toxic encephalopathy? 64 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 64 reports of Toxic encephalopathy have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 0.1% of all adverse event reports for FLUOROURACIL.
64
Reports of Toxic encephalopathy with FLUOROURACIL
0.1%
of all FLUOROURACIL reports
8
Deaths
27
Hospitalizations
How Dangerous Is Toxic encephalopathy From FLUOROURACIL?
Of the 64 reports, 8 (12.5%) resulted in death, 27 (42.2%) required hospitalization, and 18 (28.1%) were considered life-threatening.
Is Toxic encephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FLUOROURACIL. However, 64 reports have been filed with the FAERS database.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Neutropenia (4,400)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
What Other Drugs Cause Toxic encephalopathy?
METRONIDAZOLE (548)
VALACYCLOVIR (384)
BACLOFEN (182)
ACYCLOVIR (168)
METHOTREXATE (142)
METFORMIN (137)
VALPROIC ACID (124)
TACROLIMUS (118)
IFOSFAMIDE (116)
DIAZEPAM (91)
Which FLUOROURACIL Alternatives Have Lower Toxic encephalopathy Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE