Does FOSFOMYCIN Cause Toxic epidermal necrolysis? 34 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 34 reports of Toxic epidermal necrolysis have been filed in association with FOSFOMYCIN (Contepo). This represents 4.1% of all adverse event reports for FOSFOMYCIN.
34
Reports of Toxic epidermal necrolysis with FOSFOMYCIN
4.1%
of all FOSFOMYCIN reports
14
Deaths
25
Hospitalizations
How Dangerous Is Toxic epidermal necrolysis From FOSFOMYCIN?
Of the 34 reports, 14 (41.2%) resulted in death, 25 (73.5%) required hospitalization, and 6 (17.6%) were considered life-threatening.
Is Toxic epidermal necrolysis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FOSFOMYCIN. However, 34 reports have been filed with the FAERS database.
What Other Side Effects Does FOSFOMYCIN Cause?
Drug ineffective (105)
Diarrhoea (98)
Off label use (68)
Pathogen resistance (66)
Pyrexia (66)
Drug resistance (63)
Acute kidney injury (52)
Urinary tract infection (51)
Drug reaction with eosinophilia and systemic symptoms (50)
Nausea (50)
What Other Drugs Cause Toxic epidermal necrolysis?
ACETAMINOPHEN (980)
LAMOTRIGINE (941)
ALLOPURINOL (858)
IBUPROFEN (764)
SULFAMETHOXAZOLE\TRIMETHOPRIM (592)
CIPROFLOXACIN (576)
FUROSEMIDE (521)
VANCOMYCIN (515)
PIPERACILLIN\TAZOBACTAM (490)
PEMBROLIZUMAB (444)
Which FOSFOMYCIN Alternatives Have Lower Toxic epidermal necrolysis Risk?
FOSFOMYCIN vs FOSFOMYCIN TROMETHAMINE
FOSFOMYCIN vs FOSINOPRIL
FOSFOMYCIN vs FOSPHENYTOIN
FOSFOMYCIN vs FOSTAMATINIB
FOSFOMYCIN vs FOSTEMSAVIR TROMETHAMINE