Does GIVOSIRAN Cause Pruritus? 9 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 9 reports of Pruritus have been filed in association with GIVOSIRAN (GIVLAARI). This represents 0.7% of all adverse event reports for GIVOSIRAN.
9
Reports of Pruritus with GIVOSIRAN
0.7%
of all GIVOSIRAN reports
0
Deaths
5
Hospitalizations
How Dangerous Is Pruritus From GIVOSIRAN?
Of the 9 reports, 5 (55.6%) required hospitalization.
Is Pruritus Listed in the Official Label?
Yes, Pruritus is listed as a known adverse reaction in the official FDA drug label for GIVOSIRAN.
What Other Side Effects Does GIVOSIRAN Cause?
Porphyria acute (381)
Hospitalisation (141)
Nausea (91)
Product dose omission issue (85)
Fatigue (84)
Therapy interrupted (83)
Pain (74)
Intentional dose omission (63)
Abdominal pain (62)
Vomiting (58)
What Other Drugs Cause Pruritus?
DUPILUMAB (44,279)
ADAPALENE (12,072)
ADALIMUMAB (9,644)
AVOBENZONE\OCTISALATE\OCTOCRYLENE (9,439)
SECUKINUMAB (8,755)
ETANERCEPT (8,047)
METHOTREXATE (7,526)
LENALIDOMIDE (6,304)
TOCILIZUMAB (5,973)
RITUXIMAB (5,548)
Which GIVOSIRAN Alternatives Have Lower Pruritus Risk?
GIVOSIRAN vs GLASDEGIB
GIVOSIRAN vs GLATIRAMER
GIVOSIRAN vs GLECAPREVIR\PIBRENTASVIR
GIVOSIRAN vs GLEEVEC
GIVOSIRAN vs GLICLAZIDE