Does HUMAN C1-ESTERASE INHIBITOR Cause Hypercholesterolaemia? 438 Reports in FDA Database

Q: Does HUMAN C1-ESTERASE INHIBITOR cause Hypercholesterolaemia?

438 reports of Hypercholesterolaemia have been filed with the FDA for HUMAN C1-ESTERASE INHIBITOR, representing 3.1% of all HUMAN C1-ESTERASE INHIBITOR adverse event reports.

Q: How dangerous is Hypercholesterolaemia from HUMAN C1-ESTERASE INHIBITOR?

Of 438 reports, 438 (100.0%) resulted in death and 355 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 438 reports of Hypercholesterolaemia have been filed in association with HUMAN C1-ESTERASE INHIBITOR (Cinryze). This represents 3.1% of all adverse event reports for HUMAN C1-ESTERASE INHIBITOR.

438

Reports of Hypercholesterolaemia with HUMAN C1-ESTERASE INHIBITOR

3.1%

of all HUMAN C1-ESTERASE INHIBITOR reports

438

Deaths

355

Hospitalizations

How Dangerous Is Hypercholesterolaemia From HUMAN C1-ESTERASE INHIBITOR?

Of the 438 reports, 438 (100.0%) resulted in death, 355 (81.1%) required hospitalization, and 362 (82.6%) were considered life-threatening.

Is Hypercholesterolaemia Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for HUMAN C1-ESTERASE INHIBITOR. However, 438 reports have been filed with the FAERS database.

What Other Side Effects Does HUMAN C1-ESTERASE INHIBITOR Cause?

Hereditary angioedema (5,572) No adverse event (1,660) Off label use (1,614) Drug ineffective (1,426) Intentional product use issue (1,117) Product use in unapproved indication (1,003) Weight increased (897) Maternal exposure during pregnancy (869) Pain (822) Condition aggravated (775)

What Other Drugs Cause Hypercholesterolaemia?

ALENDRONATE (1,607) METHOTREXATE (1,547) TOCILIZUMAB (1,483) ADALIMUMAB (1,479) ABATACEPT (1,410) RITUXIMAB (1,389) PREDNISONE (1,377) INFLIXIMAB (1,338) DICLOFENAC (1,331) LEFLUNOMIDE (1,322)

Which HUMAN C1-ESTERASE INHIBITOR Alternatives Have Lower Hypercholesterolaemia Risk?

HUMAN C1-ESTERASE INHIBITOR vs HUMAN COAGULATION FACTOR VIII/VON WILLEBRAND FACTOR COMPLEX HUMAN C1-ESTERASE INHIBITOR vs HUMAN CYTOMEGALOVIRUS IMMUNE GLOBULIN HUMAN C1-ESTERASE INHIBITOR vs HUMAN HEPATITIS B VIRUS IMMUNE GLOBULIN HUMAN C1-ESTERASE INHIBITOR vs HUMAN IMMUNOGLOBULIN G HUMAN C1-ESTERASE INHIBITOR vs HUMAN IMMUNOGLOBULIN G\HYALURONIDASE

HUMAN C1-ESTERASE INHIBITOR Full Profile All Hypercholesterolaemia Reports All Drugs Causing Hypercholesterolaemia HUMAN C1-ESTERASE INHIBITOR Demographics