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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Does HUMAN C1-ESTERASE INHIBITOR Cause Off label use? 1,614 Reports in FDA Database

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According to the FDA Adverse Event Reporting System (FAERS), 1,614 reports of Off label use have been filed in association with HUMAN C1-ESTERASE INHIBITOR (Cinryze). This represents 11.3% of all adverse event reports for HUMAN C1-ESTERASE INHIBITOR.

1,614
Reports of Off label use with HUMAN C1-ESTERASE INHIBITOR
11.3%
of all HUMAN C1-ESTERASE INHIBITOR reports
808
Deaths
964
Hospitalizations

How Dangerous Is Off label use From HUMAN C1-ESTERASE INHIBITOR?

Of the 1,614 reports, 808 (50.1%) resulted in death, 964 (59.7%) required hospitalization, and 784 (48.6%) were considered life-threatening.

Is Off label use Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for HUMAN C1-ESTERASE INHIBITOR. However, 1,614 reports have been filed with the FAERS database.

What Other Side Effects Does HUMAN C1-ESTERASE INHIBITOR Cause?

Hereditary angioedema (5,572) No adverse event (1,660) Drug ineffective (1,426) Intentional product use issue (1,117) Product use in unapproved indication (1,003) Weight increased (897) Maternal exposure during pregnancy (869) Pain (822) Condition aggravated (775) Swelling (737)

What Other Drugs Cause Off label use?

RITUXIMAB (39,751) INFLIXIMAB (34,801) DENOSUMAB (34,612) METHOTREXATE (24,020) VEDOLIZUMAB (21,017) ETANERCEPT (20,178) TOCILIZUMAB (18,256) PREDNISONE (17,867) LENALIDOMIDE (17,017) ADALIMUMAB (16,417)

Which HUMAN C1-ESTERASE INHIBITOR Alternatives Have Lower Off label use Risk?

HUMAN C1-ESTERASE INHIBITOR vs HUMAN COAGULATION FACTOR VIII/VON WILLEBRAND FACTOR COMPLEX HUMAN C1-ESTERASE INHIBITOR vs HUMAN CYTOMEGALOVIRUS IMMUNE GLOBULIN HUMAN C1-ESTERASE INHIBITOR vs HUMAN HEPATITIS B VIRUS IMMUNE GLOBULIN HUMAN C1-ESTERASE INHIBITOR vs HUMAN IMMUNOGLOBULIN G HUMAN C1-ESTERASE INHIBITOR vs HUMAN IMMUNOGLOBULIN G\HYALURONIDASE

Related Pages

HUMAN C1-ESTERASE INHIBITOR Full Profile All Off label use Reports All Drugs Causing Off label use HUMAN C1-ESTERASE INHIBITOR Demographics