Does HUMAN C1-ESTERASE INHIBITOR Cause Injection site reaction? 331 Reports in FDA Database

Q: Does HUMAN C1-ESTERASE INHIBITOR cause Injection site reaction?

331 reports of Injection site reaction have been filed with the FDA for HUMAN C1-ESTERASE INHIBITOR, representing 2.3% of all HUMAN C1-ESTERASE INHIBITOR adverse event reports.

Q: How dangerous is Injection site reaction from HUMAN C1-ESTERASE INHIBITOR?

Of 331 reports, 293 (88.5%) resulted in death and 294 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 331 reports of Injection site reaction have been filed in association with HUMAN C1-ESTERASE INHIBITOR (Cinryze). This represents 2.3% of all adverse event reports for HUMAN C1-ESTERASE INHIBITOR.

331

Reports of Injection site reaction with HUMAN C1-ESTERASE INHIBITOR

2.3%

of all HUMAN C1-ESTERASE INHIBITOR reports

293

Deaths

294

Hospitalizations

How Dangerous Is Injection site reaction From HUMAN C1-ESTERASE INHIBITOR?

Of the 331 reports, 293 (88.5%) resulted in death, 294 (88.8%) required hospitalization, and 289 (87.3%) were considered life-threatening.

Is Injection site reaction Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for HUMAN C1-ESTERASE INHIBITOR. However, 331 reports have been filed with the FAERS database.

What Other Side Effects Does HUMAN C1-ESTERASE INHIBITOR Cause?

Hereditary angioedema (5,572) No adverse event (1,660) Off label use (1,614) Drug ineffective (1,426) Intentional product use issue (1,117) Product use in unapproved indication (1,003) Weight increased (897) Maternal exposure during pregnancy (869) Pain (822) Condition aggravated (775)

What Other Drugs Cause Injection site reaction?

ETANERCEPT (9,962) ADALIMUMAB (4,375) NALTREXONE (4,360) DUPILUMAB (4,129) GLATIRAMER (3,317) IXEKIZUMAB (1,701) METHOTREXATE (1,663) TIRZEPATIDE (1,389) TOCILIZUMAB (1,343) CERTOLIZUMAB PEGOL (1,253)

Which HUMAN C1-ESTERASE INHIBITOR Alternatives Have Lower Injection site reaction Risk?

HUMAN C1-ESTERASE INHIBITOR vs HUMAN COAGULATION FACTOR VIII/VON WILLEBRAND FACTOR COMPLEX HUMAN C1-ESTERASE INHIBITOR vs HUMAN CYTOMEGALOVIRUS IMMUNE GLOBULIN HUMAN C1-ESTERASE INHIBITOR vs HUMAN HEPATITIS B VIRUS IMMUNE GLOBULIN HUMAN C1-ESTERASE INHIBITOR vs HUMAN IMMUNOGLOBULIN G HUMAN C1-ESTERASE INHIBITOR vs HUMAN IMMUNOGLOBULIN G\HYALURONIDASE

HUMAN C1-ESTERASE INHIBITOR Full Profile All Injection site reaction Reports All Drugs Causing Injection site reaction HUMAN C1-ESTERASE INHIBITOR Demographics