Does METHOTREXATE Cause Injection site reaction? 1,663 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,663 reports of Injection site reaction have been filed in association with METHOTREXATE (Methotrexate). This represents 0.7% of all adverse event reports for METHOTREXATE.
1,663
Reports of Injection site reaction with METHOTREXATE
0.7%
of all METHOTREXATE reports
318
Deaths
694
Hospitalizations
How Dangerous Is Injection site reaction From METHOTREXATE?
Of the 1,663 reports, 318 (19.1%) resulted in death, 694 (41.7%) required hospitalization, and 316 (19.0%) were considered life-threatening.
Is Injection site reaction Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 1,663 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Injection site reaction?
ETANERCEPT (9,962)
ADALIMUMAB (4,375)
NALTREXONE (4,360)
DUPILUMAB (4,129)
GLATIRAMER (3,317)
IXEKIZUMAB (1,701)
TIRZEPATIDE (1,389)
TOCILIZUMAB (1,343)
CERTOLIZUMAB PEGOL (1,253)
ABATACEPT (1,190)
Which METHOTREXATE Alternatives Have Lower Injection site reaction Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA