Does HUMAN C1-ESTERASE INHIBITOR Cause Sepsis? 84 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 84 reports of Sepsis have been filed in association with HUMAN C1-ESTERASE INHIBITOR (Cinryze). This represents 0.6% of all adverse event reports for HUMAN C1-ESTERASE INHIBITOR.
84
Reports of Sepsis with HUMAN C1-ESTERASE INHIBITOR
0.6%
of all HUMAN C1-ESTERASE INHIBITOR reports
2
Deaths
75
Hospitalizations
How Dangerous Is Sepsis From HUMAN C1-ESTERASE INHIBITOR?
Of the 84 reports, 2 (2.4%) resulted in death, 75 (89.3%) required hospitalization, and 1 (1.2%) were considered life-threatening.
Is Sepsis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for HUMAN C1-ESTERASE INHIBITOR. However, 84 reports have been filed with the FAERS database.
What Other Side Effects Does HUMAN C1-ESTERASE INHIBITOR Cause?
Hereditary angioedema (5,572)
No adverse event (1,660)
Off label use (1,614)
Drug ineffective (1,426)
Intentional product use issue (1,117)
Product use in unapproved indication (1,003)
Weight increased (897)
Maternal exposure during pregnancy (869)
Pain (822)
Condition aggravated (775)
What Other Drugs Cause Sepsis?
RITUXIMAB (4,043)
CYCLOPHOSPHAMIDE (4,041)
METHOTREXATE (3,933)
ADALIMUMAB (3,169)
DEXAMETHASONE (3,150)
LENALIDOMIDE (2,956)
VINCRISTINE (2,791)
DOXORUBICIN (2,740)
PREDNISONE (2,634)
PREDNISOLONE (2,281)
Which HUMAN C1-ESTERASE INHIBITOR Alternatives Have Lower Sepsis Risk?
HUMAN C1-ESTERASE INHIBITOR vs HUMAN COAGULATION FACTOR VIII/VON WILLEBRAND FACTOR COMPLEX
HUMAN C1-ESTERASE INHIBITOR vs HUMAN CYTOMEGALOVIRUS IMMUNE GLOBULIN
HUMAN C1-ESTERASE INHIBITOR vs HUMAN HEPATITIS B VIRUS IMMUNE GLOBULIN
HUMAN C1-ESTERASE INHIBITOR vs HUMAN IMMUNOGLOBULIN G
HUMAN C1-ESTERASE INHIBITOR vs HUMAN IMMUNOGLOBULIN G\HYALURONIDASE