Does HUMAN C1-ESTERASE INHIBITOR Cause Treatment failure? 370 Reports in FDA Database

Q: Does HUMAN C1-ESTERASE INHIBITOR cause Treatment failure?

370 reports of Treatment failure have been filed with the FDA for HUMAN C1-ESTERASE INHIBITOR, representing 2.6% of all HUMAN C1-ESTERASE INHIBITOR adverse event reports.

Q: How dangerous is Treatment failure from HUMAN C1-ESTERASE INHIBITOR?

Of 370 reports, 361 (97.6%) resulted in death and 296 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 370 reports of Treatment failure have been filed in association with HUMAN C1-ESTERASE INHIBITOR (Cinryze). This represents 2.6% of all adverse event reports for HUMAN C1-ESTERASE INHIBITOR.

370

Reports of Treatment failure with HUMAN C1-ESTERASE INHIBITOR

2.6%

of all HUMAN C1-ESTERASE INHIBITOR reports

361

Deaths

296

Hospitalizations

How Dangerous Is Treatment failure From HUMAN C1-ESTERASE INHIBITOR?

Of the 370 reports, 361 (97.6%) resulted in death, 296 (80.0%) required hospitalization, and 297 (80.3%) were considered life-threatening.

Is Treatment failure Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for HUMAN C1-ESTERASE INHIBITOR. However, 370 reports have been filed with the FAERS database.

What Other Side Effects Does HUMAN C1-ESTERASE INHIBITOR Cause?

Hereditary angioedema (5,572) No adverse event (1,660) Off label use (1,614) Drug ineffective (1,426) Intentional product use issue (1,117) Product use in unapproved indication (1,003) Weight increased (897) Maternal exposure during pregnancy (869) Pain (822) Condition aggravated (775)

What Other Drugs Cause Treatment failure?

METHOTREXATE (14,672) ETANERCEPT (11,893) ADALIMUMAB (9,990) ABATACEPT (9,301) RITUXIMAB (9,217) TOCILIZUMAB (9,097) HYDROXYCHLOROQUINE (8,786) LEFLUNOMIDE (8,686) INFLIXIMAB (8,535) SULFASALAZINE (7,423)

Which HUMAN C1-ESTERASE INHIBITOR Alternatives Have Lower Treatment failure Risk?

HUMAN C1-ESTERASE INHIBITOR vs HUMAN COAGULATION FACTOR VIII/VON WILLEBRAND FACTOR COMPLEX HUMAN C1-ESTERASE INHIBITOR vs HUMAN CYTOMEGALOVIRUS IMMUNE GLOBULIN HUMAN C1-ESTERASE INHIBITOR vs HUMAN HEPATITIS B VIRUS IMMUNE GLOBULIN HUMAN C1-ESTERASE INHIBITOR vs HUMAN IMMUNOGLOBULIN G HUMAN C1-ESTERASE INHIBITOR vs HUMAN IMMUNOGLOBULIN G\HYALURONIDASE

HUMAN C1-ESTERASE INHIBITOR Full Profile All Treatment failure Reports All Drugs Causing Treatment failure HUMAN C1-ESTERASE INHIBITOR Demographics