Treatment failure: Which Medications Cause It? (74,247 Reports Across 1,374 Drugs)
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Treatment failure has been reported as an adverse event with 1,374 different drugs in the FDA's FAERS database, with 74,247 total reports. 4,099 of these reports resulted in death.The drugs most commonly associated with Treatment failure are METHOTREXATE, ETANERCEPT, and ADALIMUMAB.
74,247
Total Reports
1,374
Drugs Involved
4,099
Deaths
8,696
Hospitalizations
49.4 yrs
Average Patient Age
64.3% / 35.7%
Female / Male
Which Drugs Cause Treatment failure Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| METHOTREXATE | 14,672 | 5.8% | 1,172 | 2,598 | 1,447 |
| ETANERCEPT | 11,893 | 3.3% | 906 | 1,953 | 1,101 |
| ADALIMUMAB | 9,990 | 2.0% | 1,111 | 2,183 | 1,317 |
| ABATACEPT | 9,301 | 8.0% | 1,071 | 2,243 | 1,369 |
| RITUXIMAB | 9,217 | 5.2% | 1,370 | 2,432 | 1,495 |
| TOCILIZUMAB | 9,097 | 9.2% | 1,231 | 2,236 | 1,331 |
| HYDROXYCHLOROQUINE | 8,786 | 13.2% | 1,060 | 2,228 | 1,288 |
| LEFLUNOMIDE | 8,686 | 15.4% | 1,113 | 2,239 | 1,377 |
| INFLIXIMAB | 8,535 | 6.1% | 1,171 | 2,189 | 1,331 |
| SULFASALAZINE | 7,423 | 18.5% | 1,027 | 2,089 | 1,288 |
| PREDNISONE | 6,244 | 3.9% | 1,229 | 1,847 | 1,441 |
| LATANOPROST | 5,781 | 37.6% | 0 | 0 | 0 |
| GOLIMUMAB | 5,684 | 8.2% | 996 | 1,800 | 1,263 |
| CERTOLIZUMAB PEGOL | 5,337 | 5.4% | 957 | 1,640 | 1,217 |
| TOFACITINIB | 5,116 | 3.3% | 1,011 | 1,660 | 1,247 |
| OLOPATADINE | 4,685 | 53.3% | 0 | 1 | 0 |
| DICLOFENAC | 4,185 | 4.8% | 1,166 | 1,413 | 1,307 |
| TIMOLOL | 3,690 | 49.5% | 0 | 1 | 0 |
| FOLIC ACID | 3,598 | 15.7% | 1,016 | 1,396 | 1,247 |
| SECUKINUMAB | 3,548 | 2.4% | 995 | 1,262 | 1,184 |