Does HUMAN C1-ESTERASE INHIBITOR Cause Underdose? 269 Reports in FDA Database

Q: Does HUMAN C1-ESTERASE INHIBITOR cause Underdose?

269 reports of Underdose have been filed with the FDA for HUMAN C1-ESTERASE INHIBITOR, representing 1.9% of all HUMAN C1-ESTERASE INHIBITOR adverse event reports.

Q: How dangerous is Underdose from HUMAN C1-ESTERASE INHIBITOR?

Of 269 reports, 143 (53.2%) resulted in death and 164 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 269 reports of Underdose have been filed in association with HUMAN C1-ESTERASE INHIBITOR (Cinryze). This represents 1.9% of all adverse event reports for HUMAN C1-ESTERASE INHIBITOR.

269

Reports of Underdose with HUMAN C1-ESTERASE INHIBITOR

1.9%

of all HUMAN C1-ESTERASE INHIBITOR reports

143

Deaths

164

Hospitalizations

How Dangerous Is Underdose From HUMAN C1-ESTERASE INHIBITOR?

Of the 269 reports, 143 (53.2%) resulted in death, 164 (61.0%) required hospitalization, and 144 (53.5%) were considered life-threatening.

Is Underdose Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for HUMAN C1-ESTERASE INHIBITOR. However, 269 reports have been filed with the FAERS database.

What Other Side Effects Does HUMAN C1-ESTERASE INHIBITOR Cause?

Hereditary angioedema (5,572) No adverse event (1,660) Off label use (1,614) Drug ineffective (1,426) Intentional product use issue (1,117) Product use in unapproved indication (1,003) Weight increased (897) Maternal exposure during pregnancy (869) Pain (822) Condition aggravated (775)

What Other Drugs Cause Underdose?

ADAPALENE (5,192) AVOBENZONE\OCTISALATE\OCTOCRYLENE (3,722) INSULIN LISPRO (3,156) ETANERCEPT (3,145) GALCANEZUMAB-GNLM (2,909) ENZALUTAMIDE (2,017) FLUTICASONE\SALMETEROL (1,600) ALBUTEROL (1,593) EXENATIDE (1,571) TROFINETIDE (1,540)

Which HUMAN C1-ESTERASE INHIBITOR Alternatives Have Lower Underdose Risk?

HUMAN C1-ESTERASE INHIBITOR vs HUMAN COAGULATION FACTOR VIII/VON WILLEBRAND FACTOR COMPLEX HUMAN C1-ESTERASE INHIBITOR vs HUMAN CYTOMEGALOVIRUS IMMUNE GLOBULIN HUMAN C1-ESTERASE INHIBITOR vs HUMAN HEPATITIS B VIRUS IMMUNE GLOBULIN HUMAN C1-ESTERASE INHIBITOR vs HUMAN IMMUNOGLOBULIN G HUMAN C1-ESTERASE INHIBITOR vs HUMAN IMMUNOGLOBULIN G\HYALURONIDASE

HUMAN C1-ESTERASE INHIBITOR Full Profile All Underdose Reports All Drugs Causing Underdose HUMAN C1-ESTERASE INHIBITOR Demographics