Skip to content
Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Does HYDROCHLOROTHIAZIDE Cause Cholestasis? 146 Reports in FDA Database

Lower Your Cholesterol — The Natural Way

The Oxidized Cholesterol Strategy: a science-backed plan for heart health.

See the Strategy

According to the FDA Adverse Event Reporting System (FAERS), 146 reports of Cholestasis have been filed in association with HYDROCHLOROTHIAZIDE (Irbesartan and Hydrochlorothiazide). This represents 0.7% of all adverse event reports for HYDROCHLOROTHIAZIDE.

146
Reports of Cholestasis with HYDROCHLOROTHIAZIDE
0.7%
of all HYDROCHLOROTHIAZIDE reports
7
Deaths
110
Hospitalizations

How Dangerous Is Cholestasis From HYDROCHLOROTHIAZIDE?

Of the 146 reports, 7 (4.8%) resulted in death, 110 (75.3%) required hospitalization, and 13 (8.9%) were considered life-threatening.

Is Cholestasis Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for HYDROCHLOROTHIAZIDE. However, 146 reports have been filed with the FAERS database.

What Other Side Effects Does HYDROCHLOROTHIAZIDE Cause?

Hyponatraemia (2,138) Drug ineffective (1,889) Acute kidney injury (1,838) Nausea (1,536) Dyspnoea (1,521) Dizziness (1,469) Headache (1,419) Hypotension (1,347) Fall (1,323) Malaise (1,312)

What Other Drugs Cause Cholestasis?

ACETAMINOPHEN (1,269) ATORVASTATIN (898) PANTOPRAZOLE (535) METHOTREXATE (507) AMOXICILLIN\CLAVULANATE (480) SULFAMETHOXAZOLE\TRIMETHOPRIM (462) ENOXAPARIN (404) PIPERACILLIN\TAZOBACTAM (394) ESOMEPRAZOLE (363) NIVOLUMAB (342)

Which HYDROCHLOROTHIAZIDE Alternatives Have Lower Cholestasis Risk?

HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\IRBESARTAN HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LISINOPRIL HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LOSARTAN HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\METOPROLOL HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\NEBIVOLOL

Related Pages

HYDROCHLOROTHIAZIDE Full Profile All Cholestasis Reports All Drugs Causing Cholestasis HYDROCHLOROTHIAZIDE Demographics