Does HYDROCHLOROTHIAZIDE Cause Hypothyroidism? 164 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 164 reports of Hypothyroidism have been filed in association with HYDROCHLOROTHIAZIDE (Irbesartan and Hydrochlorothiazide). This represents 0.8% of all adverse event reports for HYDROCHLOROTHIAZIDE.
164
Reports of Hypothyroidism with HYDROCHLOROTHIAZIDE
0.8%
of all HYDROCHLOROTHIAZIDE reports
48
Deaths
108
Hospitalizations
How Dangerous Is Hypothyroidism From HYDROCHLOROTHIAZIDE?
Of the 164 reports, 48 (29.3%) resulted in death, 108 (65.9%) required hospitalization, and 115 (70.1%) were considered life-threatening.
Is Hypothyroidism Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for HYDROCHLOROTHIAZIDE. However, 164 reports have been filed with the FAERS database.
What Other Side Effects Does HYDROCHLOROTHIAZIDE Cause?
Hyponatraemia (2,138)
Drug ineffective (1,889)
Acute kidney injury (1,838)
Nausea (1,536)
Dyspnoea (1,521)
Dizziness (1,469)
Headache (1,419)
Hypotension (1,347)
Fall (1,323)
Malaise (1,312)
What Other Drugs Cause Hypothyroidism?
PEMBROLIZUMAB (2,326)
LEVOTHYROXINE (2,107)
NIVOLUMAB (1,939)
LENVATINIB (1,375)
ATEZOLIZUMAB (881)
ALBUTEROL (877)
CARBOPLATIN (830)
IPILIMUMAB (770)
AMIODARONE (764)
PREDNISONE (739)
Which HYDROCHLOROTHIAZIDE Alternatives Have Lower Hypothyroidism Risk?
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\IRBESARTAN
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LISINOPRIL
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LOSARTAN
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\METOPROLOL
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\NEBIVOLOL