Does HYDROCHLOROTHIAZIDE Cause Pathological fracture? 41 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 41 reports of Pathological fracture have been filed in association with HYDROCHLOROTHIAZIDE (Irbesartan and Hydrochlorothiazide). This represents 0.2% of all adverse event reports for HYDROCHLOROTHIAZIDE.
41
Reports of Pathological fracture with HYDROCHLOROTHIAZIDE
0.2%
of all HYDROCHLOROTHIAZIDE reports
11
Deaths
10
Hospitalizations
How Dangerous Is Pathological fracture From HYDROCHLOROTHIAZIDE?
Of the 41 reports, 11 (26.8%) resulted in death, 10 (24.4%) required hospitalization, and 9 (22.0%) were considered life-threatening.
Is Pathological fracture Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for HYDROCHLOROTHIAZIDE. However, 41 reports have been filed with the FAERS database.
What Other Side Effects Does HYDROCHLOROTHIAZIDE Cause?
Hyponatraemia (2,138)
Drug ineffective (1,889)
Acute kidney injury (1,838)
Nausea (1,536)
Dyspnoea (1,521)
Dizziness (1,469)
Headache (1,419)
Hypotension (1,347)
Fall (1,323)
Malaise (1,312)
What Other Drugs Cause Pathological fracture?
DENOSUMAB (634)
LENALIDOMIDE (260)
DEXAMETHASONE (201)
ALENDRONATE (200)
ZOLEDRONIC ACID (185)
RISEDRONATE (110)
ADALIMUMAB (93)
LETROZOLE (87)
RITUXIMAB (87)
CYCLOPHOSPHAMIDE (85)
Which HYDROCHLOROTHIAZIDE Alternatives Have Lower Pathological fracture Risk?
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\IRBESARTAN
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LISINOPRIL
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LOSARTAN
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\METOPROLOL
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\NEBIVOLOL