Does HYDROXYUREA Cause Extremity necrosis? 12 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 12 reports of Extremity necrosis have been filed in association with HYDROXYUREA (Hydroxyurea). This represents 0.2% of all adverse event reports for HYDROXYUREA.
12
Reports of Extremity necrosis with HYDROXYUREA
0.2%
of all HYDROXYUREA reports
1
Deaths
11
Hospitalizations
How Dangerous Is Extremity necrosis From HYDROXYUREA?
Of the 12 reports, 1 (8.3%) resulted in death, 11 (91.7%) required hospitalization.
Is Extremity necrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for HYDROXYUREA. However, 12 reports have been filed with the FAERS database.
What Other Side Effects Does HYDROXYUREA Cause?
Off label use (519)
Anaemia (358)
Drug ineffective (356)
Fatigue (291)
Thrombocytopenia (253)
Nausea (247)
Pyrexia (243)
Diarrhoea (222)
Febrile neutropenia (202)
Intentional product use issue (201)
What Other Drugs Cause Extremity necrosis?
CANAGLIFLOZIN (95)
CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM (84)
CARBOPLATIN (46)
PEMETREXED (45)
ADALIMUMAB (42)
GEMCITABINE (40)
METHYLPREDNISOLONE (40)
EPINEPHRINE (39)
PEMBROLIZUMAB (37)
NOREPINEPHRINE (34)
Which HYDROXYUREA Alternatives Have Lower Extremity necrosis Risk?
HYDROXYUREA vs HYDROXYZINE
HYDROXYUREA vs HYDROXYZINE\HYDROXYZINE
HYDROXYUREA vs HYOSCYAMINE
HYDROXYUREA vs HYPROMELLOSE 2910
HYDROXYUREA vs IBALIZUMAB-UIYK