Does IBRUTINIB Cause Bone marrow failure? 107 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 107 reports of Bone marrow failure have been filed in association with IBRUTINIB (Imbruvica). This represents 0.1% of all adverse event reports for IBRUTINIB.
107
Reports of Bone marrow failure with IBRUTINIB
0.1%
of all IBRUTINIB reports
28
Deaths
32
Hospitalizations
How Dangerous Is Bone marrow failure From IBRUTINIB?
Of the 107 reports, 28 (26.2%) resulted in death, 32 (29.9%) required hospitalization, and 8 (7.5%) were considered life-threatening.
Is Bone marrow failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IBRUTINIB. However, 107 reports have been filed with the FAERS database.
What Other Side Effects Does IBRUTINIB Cause?
Death (8,007)
Off label use (5,446)
Fatigue (4,479)
Diarrhoea (3,903)
Atrial fibrillation (3,671)
Pneumonia (3,015)
Incorrect dose administered (2,752)
Contusion (2,712)
Fall (2,375)
Asthenia (2,200)
What Other Drugs Cause Bone marrow failure?
CYCLOPHOSPHAMIDE (1,834)
METHOTREXATE (1,401)
ETOPOSIDE (1,081)
RITUXIMAB (1,060)
CYTARABINE (1,052)
VINCRISTINE (1,001)
DOXORUBICIN (1,000)
PALBOCICLIB (951)
CARBOPLATIN (855)
BEVACIZUMAB (835)
Which IBRUTINIB Alternatives Have Lower Bone marrow failure Risk?
IBRUTINIB vs IBUPROFEN
IBRUTINIB vs IBUPROFEN LYSINE
IBRUTINIB vs IBUPROFEN UNKNOWN PRODUCT
IBRUTINIB vs IBUPROFEN\IBUPROFEN
IBRUTINIB vs IBUPROFEN\PHENYLEPHRINE