Does IBRUTINIB Cause Clostridium difficile infection? 150 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 150 reports of Clostridium difficile infection have been filed in association with IBRUTINIB (Imbruvica). This represents 0.2% of all adverse event reports for IBRUTINIB.
150
Reports of Clostridium difficile infection with IBRUTINIB
0.2%
of all IBRUTINIB reports
18
Deaths
120
Hospitalizations
How Dangerous Is Clostridium difficile infection From IBRUTINIB?
Of the 150 reports, 18 (12.0%) resulted in death, 120 (80.0%) required hospitalization, and 2 (1.3%) were considered life-threatening.
Is Clostridium difficile infection Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IBRUTINIB. However, 150 reports have been filed with the FAERS database.
What Other Side Effects Does IBRUTINIB Cause?
Death (8,007)
Off label use (5,446)
Fatigue (4,479)
Diarrhoea (3,903)
Atrial fibrillation (3,671)
Pneumonia (3,015)
Incorrect dose administered (2,752)
Contusion (2,712)
Fall (2,375)
Asthenia (2,200)
What Other Drugs Cause Clostridium difficile infection?
ADALIMUMAB (1,502)
INFLIXIMAB (1,419)
VEDOLIZUMAB (1,130)
LENALIDOMIDE (814)
VANCOMYCIN (743)
METRONIDAZOLE (619)
PREDNISONE (618)
METHOTREXATE (588)
RITUXIMAB (532)
CIPROFLOXACIN (508)
Which IBRUTINIB Alternatives Have Lower Clostridium difficile infection Risk?
IBRUTINIB vs IBUPROFEN
IBRUTINIB vs IBUPROFEN LYSINE
IBRUTINIB vs IBUPROFEN UNKNOWN PRODUCT
IBRUTINIB vs IBUPROFEN\IBUPROFEN
IBRUTINIB vs IBUPROFEN\PHENYLEPHRINE