Does IBRUTINIB Cause Progressive multifocal leukoencephalopathy? 91 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 91 reports of Progressive multifocal leukoencephalopathy have been filed in association with IBRUTINIB (Imbruvica). This represents 0.1% of all adverse event reports for IBRUTINIB.
91
Reports of Progressive multifocal leukoencephalopathy with IBRUTINIB
0.1%
of all IBRUTINIB reports
50
Deaths
39
Hospitalizations
How Dangerous Is Progressive multifocal leukoencephalopathy From IBRUTINIB?
Of the 91 reports, 50 (54.9%) resulted in death, 39 (42.9%) required hospitalization, and 15 (16.5%) were considered life-threatening.
Is Progressive multifocal leukoencephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IBRUTINIB. However, 91 reports have been filed with the FAERS database.
What Other Side Effects Does IBRUTINIB Cause?
Death (8,007)
Off label use (5,446)
Fatigue (4,479)
Diarrhoea (3,903)
Atrial fibrillation (3,671)
Pneumonia (3,015)
Incorrect dose administered (2,752)
Contusion (2,712)
Fall (2,375)
Asthenia (2,200)
What Other Drugs Cause Progressive multifocal leukoencephalopathy?
NATALIZUMAB (1,668)
RITUXIMAB (1,647)
CYCLOPHOSPHAMIDE (782)
PREDNISONE (606)
PREDNISOLONE (439)
TACROLIMUS (438)
METHOTREXATE (428)
DOXORUBICIN (421)
MYCOPHENOLATE MOFETIL (414)
VINCRISTINE (376)
Which IBRUTINIB Alternatives Have Lower Progressive multifocal leukoencephalopathy Risk?
IBRUTINIB vs IBUPROFEN
IBRUTINIB vs IBUPROFEN LYSINE
IBRUTINIB vs IBUPROFEN UNKNOWN PRODUCT
IBRUTINIB vs IBUPROFEN\IBUPROFEN
IBRUTINIB vs IBUPROFEN\PHENYLEPHRINE