Does IBRUTINIB Cause Pruritus? 730 Reports in FDA Database

Q: Does IBRUTINIB cause Pruritus?

730 reports of Pruritus have been filed with the FDA for IBRUTINIB, representing 1.0% of all IBRUTINIB adverse event reports.

Q: How dangerous is Pruritus from IBRUTINIB?

Of 730 reports, 24 (3.3%) resulted in death and 178 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 730 reports of Pruritus have been filed in association with IBRUTINIB (Imbruvica). This represents 1.0% of all adverse event reports for IBRUTINIB.

730

Reports of Pruritus with IBRUTINIB

1.0%

of all IBRUTINIB reports

Deaths

178

Hospitalizations

How Dangerous Is Pruritus From IBRUTINIB?

Of the 730 reports, 24 (3.3%) resulted in death, 178 (24.4%) required hospitalization, and 7 (1.0%) were considered life-threatening.

Is Pruritus Listed in the Official Label?

Yes, Pruritus is listed as a known adverse reaction in the official FDA drug label for IBRUTINIB.

What Other Side Effects Does IBRUTINIB Cause?

Death (8,007) Off label use (5,446) Fatigue (4,479) Diarrhoea (3,903) Atrial fibrillation (3,671) Pneumonia (3,015) Incorrect dose administered (2,752) Contusion (2,712) Fall (2,375) Asthenia (2,200)

What Other Drugs Cause Pruritus?

DUPILUMAB (44,279) ADAPALENE (12,072) ADALIMUMAB (9,644) AVOBENZONE\OCTISALATE\OCTOCRYLENE (9,439) SECUKINUMAB (8,755) ETANERCEPT (8,047) METHOTREXATE (7,526) LENALIDOMIDE (6,304) TOCILIZUMAB (5,973) RITUXIMAB (5,548)

Which IBRUTINIB Alternatives Have Lower Pruritus Risk?

IBRUTINIB vs IBUPROFEN IBRUTINIB vs IBUPROFEN LYSINE IBRUTINIB vs IBUPROFEN UNKNOWN PRODUCT IBRUTINIB vs IBUPROFEN\IBUPROFEN IBRUTINIB vs IBUPROFEN\PHENYLEPHRINE

IBRUTINIB Full Profile All Pruritus Reports All Drugs Causing Pruritus IBRUTINIB Demographics