Does IMIPENEM Cause Clostridium difficile colitis? 40 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 40 reports of Clostridium difficile colitis have been filed in association with IMIPENEM. This represents 2.1% of all adverse event reports for IMIPENEM.
40
Reports of Clostridium difficile colitis with IMIPENEM
2.1%
of all IMIPENEM reports
23
Deaths
32
Hospitalizations
How Dangerous Is Clostridium difficile colitis From IMIPENEM?
Of the 40 reports, 23 (57.5%) resulted in death, 32 (80.0%) required hospitalization, and 16 (40.0%) were considered life-threatening.
Is Clostridium difficile colitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IMIPENEM. However, 40 reports have been filed with the FAERS database.
What Other Side Effects Does IMIPENEM Cause?
Drug ineffective (351)
Off label use (202)
Condition aggravated (138)
Vomiting (137)
Drug resistance (117)
Nausea (111)
Dyspnoea (97)
Diarrhoea (90)
Pyrexia (90)
Product use in unapproved indication (85)
What Other Drugs Cause Clostridium difficile colitis?
CYCLOPHOSPHAMIDE (717)
PREDNISONE (619)
DEXAMETHASONE (575)
METHOTREXATE (562)
ETOPOSIDE (503)
CYTARABINE (489)
VINCRISTINE (482)
LENALIDOMIDE (388)
METHYLPREDNISOLONE (385)
CIPROFLOXACIN (378)
Which IMIPENEM Alternatives Have Lower Clostridium difficile colitis Risk?
IMIPENEM vs IMIPRAMINE
IMIPENEM vs IMIQUIMOD
IMIPENEM vs IMITREX
IMIPENEM vs IMMUNE GLOBULIN NOS
IMIPENEM vs IMPLANON