Does INCLISIRAN Cause Cholestasis? 12 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 12 reports of Cholestasis have been filed in association with INCLISIRAN (LEQVIO). This represents 0.2% of all adverse event reports for INCLISIRAN.
12
Reports of Cholestasis with INCLISIRAN
0.2%
of all INCLISIRAN reports
0
Deaths
11
Hospitalizations
How Dangerous Is Cholestasis From INCLISIRAN?
Of the 12 reports, 11 (91.7%) required hospitalization, and 11 (91.7%) were considered life-threatening.
Is Cholestasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for INCLISIRAN. However, 12 reports have been filed with the FAERS database.
What Other Side Effects Does INCLISIRAN Cause?
Arthralgia (689)
Myalgia (518)
Injection site pain (488)
Low density lipoprotein increased (423)
Pain in extremity (417)
Pain (342)
Fatigue (325)
Drug ineffective (318)
Diarrhoea (309)
Dyspnoea (297)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
AMOXICILLIN\CLAVULANATE (480)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
Which INCLISIRAN Alternatives Have Lower Cholestasis Risk?
INCLISIRAN vs INCOBOTULINUMTOXINA
INCLISIRAN vs INDACATEROL
INCLISIRAN vs INDAPAMIDE
INCLISIRAN vs INDAPAMIDE\PERINDOPRIL
INCLISIRAN vs INDAPAMIDE\PERINDOPRIL ARGININE