Does IPILIMUMAB Cause Cholestasis? 126 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 126 reports of Cholestasis have been filed in association with IPILIMUMAB (YERVOY). This represents 0.3% of all adverse event reports for IPILIMUMAB.
126
Reports of Cholestasis with IPILIMUMAB
0.3%
of all IPILIMUMAB reports
16
Deaths
89
Hospitalizations
How Dangerous Is Cholestasis From IPILIMUMAB?
Of the 126 reports, 16 (12.7%) resulted in death, 89 (70.6%) required hospitalization, and 4 (3.2%) were considered life-threatening.
Is Cholestasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IPILIMUMAB. However, 126 reports have been filed with the FAERS database.
What Other Side Effects Does IPILIMUMAB Cause?
Death (3,710)
Malignant neoplasm progression (3,296)
Diarrhoea (2,557)
Off label use (2,097)
Colitis (1,988)
Pyrexia (1,796)
Rash (1,556)
Fatigue (1,447)
Intentional product use issue (1,329)
Nausea (1,169)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
AMOXICILLIN\CLAVULANATE (480)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
Which IPILIMUMAB Alternatives Have Lower Cholestasis Risk?
IPILIMUMAB vs IPRAGLIFLOZIN L-PROLINE
IPILIMUMAB vs IPRATROPIUM
IPILIMUMAB vs IPRATROPIUM\IPRATROPIUM ANHYDROUS
IPILIMUMAB vs IPTACOPAN
IPILIMUMAB vs IRBESARTAN