IRINOTECAN for Chemotherapy: Side Effects & Safety Data
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There are 398 adverse event reports in the FDA FAERS database where IRINOTECAN was used for Chemotherapy.
Most Reported Side Effects for IRINOTECAN
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Diarrhoea | 4,157 | 14.9% | 558 | 1,893 |
| Neutropenia | 2,533 | 9.1% | 343 | 655 |
| Nausea | 2,374 | 8.5% | 228 | 1,029 |
| Disease progression | 2,018 | 7.2% | 628 | 271 |
| Off label use | 2,018 | 7.2% | 345 | 630 |
| Vomiting | 1,944 | 7.0% | 225 | 1,057 |
| Fatigue | 1,515 | 5.4% | 205 | 557 |
| Febrile neutropenia | 1,357 | 4.9% | 224 | 805 |
| Anaemia | 1,231 | 4.4% | 195 | 462 |
| Thrombocytopenia | 1,214 | 4.3% | 188 | 305 |
| Neuropathy peripheral | 1,207 | 4.3% | 75 | 183 |
| Asthenia | 1,154 | 4.1% | 157 | 557 |
| Pyrexia | 1,145 | 4.1% | 124 | 831 |
| Drug ineffective | 1,133 | 4.1% | 277 | 238 |
| Decreased appetite | 1,119 | 4.0% | 165 | 532 |
Other Indications for IRINOTECAN
Colorectal cancer metastatic (4,655)
Pancreatic carcinoma (2,128)
Colon cancer (2,105)
Product used for unknown indication (2,042)
Colorectal cancer (1,446)
Adenocarcinoma of colon (1,235)
Rectal cancer (985)
Pancreatic carcinoma metastatic (977)
Adenocarcinoma pancreas (908)
Colon cancer metastatic (841)
Other Drugs Used for Chemotherapy
CYCLOPHOSPHAMIDE (3,372)
DOCETAXEL (2,134)
CARBOPLATIN (1,902)
DOXORUBICIN (1,756)
VINCRISTINE (1,743)
PACLITAXEL (1,425)
OXALIPLATIN (1,423)
METHOTREXATE (1,380)
CYTARABINE (1,355)
ETOPOSIDE (1,246)