Does IRINOTECAN Cause Coagulopathy? 51 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 51 reports of Coagulopathy have been filed in association with IRINOTECAN (Irinotecan Hydrochloride). This represents 0.2% of all adverse event reports for IRINOTECAN.
51
Reports of Coagulopathy with IRINOTECAN
0.2%
of all IRINOTECAN reports
24
Deaths
43
Hospitalizations
How Dangerous Is Coagulopathy From IRINOTECAN?
Of the 51 reports, 24 (47.1%) resulted in death, 43 (84.3%) required hospitalization, and 14 (27.5%) were considered life-threatening.
Is Coagulopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IRINOTECAN. However, 51 reports have been filed with the FAERS database.
What Other Side Effects Does IRINOTECAN Cause?
Diarrhoea (4,157)
Neutropenia (2,533)
Nausea (2,374)
Disease progression (2,018)
Off label use (2,018)
Vomiting (1,944)
Fatigue (1,515)
Febrile neutropenia (1,357)
Anaemia (1,231)
Thrombocytopenia (1,214)
What Other Drugs Cause Coagulopathy?
RIVAROXABAN (1,002)
ACETAMINOPHEN (977)
DABIGATRAN ETEXILATE (718)
ASPIRIN (674)
WARFARIN (589)
METHOTREXATE (414)
VINCRISTINE (275)
APIXABAN (271)
CYCLOPHOSPHAMIDE (240)
PREDNISONE (228)
Which IRINOTECAN Alternatives Have Lower Coagulopathy Risk?
IRINOTECAN vs IRON
IRINOTECAN vs IRON DEXTRAN
IRINOTECAN vs IRON ISOMALTOSIDE 1000
IRINOTECAN vs IRON POLYMALTOSE
IRINOTECAN vs IRON SUCROSE