Does METHOTREXATE Cause Coagulopathy? 414 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 414 reports of Coagulopathy have been filed in association with METHOTREXATE (Methotrexate). This represents 0.2% of all adverse event reports for METHOTREXATE.
414
Reports of Coagulopathy with METHOTREXATE
0.2%
of all METHOTREXATE reports
147
Deaths
289
Hospitalizations
How Dangerous Is Coagulopathy From METHOTREXATE?
Of the 414 reports, 147 (35.5%) resulted in death, 289 (69.8%) required hospitalization, and 102 (24.6%) were considered life-threatening.
Is Coagulopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 414 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Coagulopathy?
RIVAROXABAN (1,002)
ACETAMINOPHEN (977)
DABIGATRAN ETEXILATE (718)
ASPIRIN (674)
WARFARIN (589)
VINCRISTINE (275)
APIXABAN (271)
CYCLOPHOSPHAMIDE (240)
PREDNISONE (228)
IBUPROFEN (227)
Which METHOTREXATE Alternatives Have Lower Coagulopathy Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA