Does IRINOTECAN Cause Diverticulitis? 35 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 35 reports of Diverticulitis have been filed in association with IRINOTECAN (Irinotecan Hydrochloride). This represents 0.1% of all adverse event reports for IRINOTECAN.
35
Reports of Diverticulitis with IRINOTECAN
0.1%
of all IRINOTECAN reports
6
Deaths
32
Hospitalizations
How Dangerous Is Diverticulitis From IRINOTECAN?
Of the 35 reports, 6 (17.1%) resulted in death, 32 (91.4%) required hospitalization, and 10 (28.6%) were considered life-threatening.
Is Diverticulitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IRINOTECAN. However, 35 reports have been filed with the FAERS database.
What Other Side Effects Does IRINOTECAN Cause?
Diarrhoea (4,157)
Neutropenia (2,533)
Nausea (2,374)
Disease progression (2,018)
Off label use (2,018)
Vomiting (1,944)
Fatigue (1,515)
Febrile neutropenia (1,357)
Anaemia (1,231)
Thrombocytopenia (1,214)
What Other Drugs Cause Diverticulitis?
ADALIMUMAB (1,768)
METHOTREXATE (1,573)
ETANERCEPT (1,567)
TOCILIZUMAB (1,420)
ABATACEPT (996)
RITUXIMAB (956)
TOFACITINIB (853)
HYDROXYCHLOROQUINE (836)
INFLIXIMAB (818)
LEFLUNOMIDE (750)
Which IRINOTECAN Alternatives Have Lower Diverticulitis Risk?
IRINOTECAN vs IRON
IRINOTECAN vs IRON DEXTRAN
IRINOTECAN vs IRON ISOMALTOSIDE 1000
IRINOTECAN vs IRON POLYMALTOSE
IRINOTECAN vs IRON SUCROSE