Does METHOTREXATE Cause Diverticulitis? 1,573 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,573 reports of Diverticulitis have been filed in association with METHOTREXATE (Methotrexate). This represents 0.6% of all adverse event reports for METHOTREXATE.
1,573
Reports of Diverticulitis with METHOTREXATE
0.6%
of all METHOTREXATE reports
108
Deaths
701
Hospitalizations
How Dangerous Is Diverticulitis From METHOTREXATE?
Of the 1,573 reports, 108 (6.9%) resulted in death, 701 (44.6%) required hospitalization, and 326 (20.7%) were considered life-threatening.
Is Diverticulitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 1,573 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Diverticulitis?
ADALIMUMAB (1,768)
ETANERCEPT (1,567)
TOCILIZUMAB (1,420)
ABATACEPT (996)
RITUXIMAB (956)
TOFACITINIB (853)
HYDROXYCHLOROQUINE (836)
INFLIXIMAB (818)
LEFLUNOMIDE (750)
OLMESARTAN MEDOXOMIL (742)
Which METHOTREXATE Alternatives Have Lower Diverticulitis Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA