Does IRINOTECAN Cause Gene mutation? 36 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 36 reports of Gene mutation have been filed in association with IRINOTECAN (Irinotecan Hydrochloride). This represents 0.1% of all adverse event reports for IRINOTECAN.
36
Reports of Gene mutation with IRINOTECAN
0.1%
of all IRINOTECAN reports
6
Deaths
3
Hospitalizations
How Dangerous Is Gene mutation From IRINOTECAN?
Of the 36 reports, 6 (16.7%) resulted in death, 3 (8.3%) required hospitalization, and 1 (2.8%) were considered life-threatening.
Is Gene mutation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IRINOTECAN. However, 36 reports have been filed with the FAERS database.
What Other Side Effects Does IRINOTECAN Cause?
Diarrhoea (4,157)
Neutropenia (2,533)
Nausea (2,374)
Disease progression (2,018)
Off label use (2,018)
Vomiting (1,944)
Fatigue (1,515)
Febrile neutropenia (1,357)
Anaemia (1,231)
Thrombocytopenia (1,214)
What Other Drugs Cause Gene mutation?
IMATINIB (141)
CYCLOPHOSPHAMIDE (139)
RITUXIMAB (117)
DOXORUBICIN (115)
LAMIVUDINE (101)
VINCRISTINE (99)
PREDNISONE (80)
BEVACIZUMAB (71)
ETOPOSIDE (66)
DASATINIB (63)
Which IRINOTECAN Alternatives Have Lower Gene mutation Risk?
IRINOTECAN vs IRON
IRINOTECAN vs IRON DEXTRAN
IRINOTECAN vs IRON ISOMALTOSIDE 1000
IRINOTECAN vs IRON POLYMALTOSE
IRINOTECAN vs IRON SUCROSE