Does IRINOTECAN Cause Hyponatraemia? 206 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 206 reports of Hyponatraemia have been filed in association with IRINOTECAN (Irinotecan Hydrochloride). This represents 0.7% of all adverse event reports for IRINOTECAN.
206
Reports of Hyponatraemia with IRINOTECAN
0.7%
of all IRINOTECAN reports
26
Deaths
128
Hospitalizations
How Dangerous Is Hyponatraemia From IRINOTECAN?
Of the 206 reports, 26 (12.6%) resulted in death, 128 (62.1%) required hospitalization, and 13 (6.3%) were considered life-threatening.
Is Hyponatraemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IRINOTECAN. However, 206 reports have been filed with the FAERS database.
What Other Side Effects Does IRINOTECAN Cause?
Diarrhoea (4,157)
Neutropenia (2,533)
Nausea (2,374)
Disease progression (2,018)
Off label use (2,018)
Vomiting (1,944)
Fatigue (1,515)
Febrile neutropenia (1,357)
Anaemia (1,231)
Thrombocytopenia (1,214)
What Other Drugs Cause Hyponatraemia?
FUROSEMIDE (3,127)
HYDROCHLOROTHIAZIDE (2,138)
OMEPRAZOLE (1,635)
LANSOPRAZOLE (1,416)
SERTRALINE (1,332)
RAMIPRIL (1,178)
SPIRONOLACTONE (1,166)
PANTOPRAZOLE (1,134)
INDAPAMIDE (976)
AMLODIPINE (879)
Which IRINOTECAN Alternatives Have Lower Hyponatraemia Risk?
IRINOTECAN vs IRON
IRINOTECAN vs IRON DEXTRAN
IRINOTECAN vs IRON ISOMALTOSIDE 1000
IRINOTECAN vs IRON POLYMALTOSE
IRINOTECAN vs IRON SUCROSE