Does IRINOTECAN Cause Lactic acidosis? 29 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 29 reports of Lactic acidosis have been filed in association with IRINOTECAN (Irinotecan Hydrochloride). This represents 0.1% of all adverse event reports for IRINOTECAN.
29
Reports of Lactic acidosis with IRINOTECAN
0.1%
of all IRINOTECAN reports
11
Deaths
25
Hospitalizations
How Dangerous Is Lactic acidosis From IRINOTECAN?
Of the 29 reports, 11 (37.9%) resulted in death, 25 (86.2%) required hospitalization, and 4 (13.8%) were considered life-threatening.
Is Lactic acidosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IRINOTECAN. However, 29 reports have been filed with the FAERS database.
What Other Side Effects Does IRINOTECAN Cause?
Diarrhoea (4,157)
Neutropenia (2,533)
Nausea (2,374)
Disease progression (2,018)
Off label use (2,018)
Vomiting (1,944)
Fatigue (1,515)
Febrile neutropenia (1,357)
Anaemia (1,231)
Thrombocytopenia (1,214)
What Other Drugs Cause Lactic acidosis?
METFORMIN (16,316)
AMLODIPINE (886)
LINEZOLID (824)
FUROSEMIDE (698)
ACETAMINOPHEN (561)
METFORMIN\SITAGLIPTIN (557)
ALBUTEROL (467)
EMPAGLIFLOZIN (434)
RAMIPRIL (430)
BISOPROLOL (425)
Which IRINOTECAN Alternatives Have Lower Lactic acidosis Risk?
IRINOTECAN vs IRON
IRINOTECAN vs IRON DEXTRAN
IRINOTECAN vs IRON ISOMALTOSIDE 1000
IRINOTECAN vs IRON POLYMALTOSE
IRINOTECAN vs IRON SUCROSE