Does IRINOTECAN Cause Left ventricular dysfunction? 21 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 21 reports of Left ventricular dysfunction have been filed in association with IRINOTECAN (Irinotecan Hydrochloride). This represents 0.1% of all adverse event reports for IRINOTECAN.
21
Reports of Left ventricular dysfunction with IRINOTECAN
0.1%
of all IRINOTECAN reports
0
Deaths
8
Hospitalizations
How Dangerous Is Left ventricular dysfunction From IRINOTECAN?
Of the 21 reports, 8 (38.1%) required hospitalization, and 2 (9.5%) were considered life-threatening.
Is Left ventricular dysfunction Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IRINOTECAN. However, 21 reports have been filed with the FAERS database.
What Other Side Effects Does IRINOTECAN Cause?
Diarrhoea (4,157)
Neutropenia (2,533)
Nausea (2,374)
Disease progression (2,018)
Off label use (2,018)
Vomiting (1,944)
Fatigue (1,515)
Febrile neutropenia (1,357)
Anaemia (1,231)
Thrombocytopenia (1,214)
What Other Drugs Cause Left ventricular dysfunction?
DOXORUBICIN (430)
CYCLOPHOSPHAMIDE (426)
TRASTUZUMAB (401)
CLOZAPINE (231)
SACUBITRIL\VALSARTAN (231)
BISOPROLOL (225)
PERTUZUMAB (207)
RITUXIMAB (202)
DOCETAXEL (199)
VINCRISTINE (193)
Which IRINOTECAN Alternatives Have Lower Left ventricular dysfunction Risk?
IRINOTECAN vs IRON
IRINOTECAN vs IRON DEXTRAN
IRINOTECAN vs IRON ISOMALTOSIDE 1000
IRINOTECAN vs IRON POLYMALTOSE
IRINOTECAN vs IRON SUCROSE