Does IRINOTECAN Cause Pancytopenia? 257 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 257 reports of Pancytopenia have been filed in association with IRINOTECAN (Irinotecan Hydrochloride). This represents 0.9% of all adverse event reports for IRINOTECAN.
257
Reports of Pancytopenia with IRINOTECAN
0.9%
of all IRINOTECAN reports
47
Deaths
153
Hospitalizations
How Dangerous Is Pancytopenia From IRINOTECAN?
Of the 257 reports, 47 (18.3%) resulted in death, 153 (59.5%) required hospitalization, and 35 (13.6%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IRINOTECAN. However, 257 reports have been filed with the FAERS database.
What Other Side Effects Does IRINOTECAN Cause?
Diarrhoea (4,157)
Neutropenia (2,533)
Nausea (2,374)
Disease progression (2,018)
Off label use (2,018)
Vomiting (1,944)
Fatigue (1,515)
Febrile neutropenia (1,357)
Anaemia (1,231)
Thrombocytopenia (1,214)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which IRINOTECAN Alternatives Have Lower Pancytopenia Risk?
IRINOTECAN vs IRON
IRINOTECAN vs IRON DEXTRAN
IRINOTECAN vs IRON ISOMALTOSIDE 1000
IRINOTECAN vs IRON POLYMALTOSE
IRINOTECAN vs IRON SUCROSE