Does IRINOTECAN Cause Pneumatosis intestinalis? 53 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 53 reports of Pneumatosis intestinalis have been filed in association with IRINOTECAN (Irinotecan Hydrochloride). This represents 0.2% of all adverse event reports for IRINOTECAN.
53
Reports of Pneumatosis intestinalis with IRINOTECAN
0.2%
of all IRINOTECAN reports
11
Deaths
16
Hospitalizations
How Dangerous Is Pneumatosis intestinalis From IRINOTECAN?
Of the 53 reports, 11 (20.8%) resulted in death, 16 (30.2%) required hospitalization, and 4 (7.5%) were considered life-threatening.
Is Pneumatosis intestinalis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IRINOTECAN. However, 53 reports have been filed with the FAERS database.
What Other Side Effects Does IRINOTECAN Cause?
Diarrhoea (4,157)
Neutropenia (2,533)
Nausea (2,374)
Disease progression (2,018)
Off label use (2,018)
Vomiting (1,944)
Fatigue (1,515)
Febrile neutropenia (1,357)
Anaemia (1,231)
Thrombocytopenia (1,214)
What Other Drugs Cause Pneumatosis intestinalis?
METHYLPREDNISOLONE (358)
TACROLIMUS (293)
CYCLOPHOSPHAMIDE (263)
PREDNISONE (258)
MYCOPHENOLATE MOFETIL (235)
DEXAMETHASONE (227)
METHOTREXATE (221)
VINCRISTINE (220)
PREDNISOLONE (213)
ETOPOSIDE (175)
Which IRINOTECAN Alternatives Have Lower Pneumatosis intestinalis Risk?
IRINOTECAN vs IRON
IRINOTECAN vs IRON DEXTRAN
IRINOTECAN vs IRON ISOMALTOSIDE 1000
IRINOTECAN vs IRON POLYMALTOSE
IRINOTECAN vs IRON SUCROSE