Does IRINOTECAN Cause Sepsis? 526 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 526 reports of Sepsis have been filed in association with IRINOTECAN (Irinotecan Hydrochloride). This represents 1.9% of all adverse event reports for IRINOTECAN.
526
Reports of Sepsis with IRINOTECAN
1.9%
of all IRINOTECAN reports
220
Deaths
316
Hospitalizations
How Dangerous Is Sepsis From IRINOTECAN?
Of the 526 reports, 220 (41.8%) resulted in death, 316 (60.1%) required hospitalization, and 65 (12.4%) were considered life-threatening.
Is Sepsis Listed in the Official Label?
Yes, Sepsis is listed as a known adverse reaction in the official FDA drug label for IRINOTECAN.
What Other Side Effects Does IRINOTECAN Cause?
Diarrhoea (4,157)
Neutropenia (2,533)
Nausea (2,374)
Disease progression (2,018)
Off label use (2,018)
Vomiting (1,944)
Fatigue (1,515)
Febrile neutropenia (1,357)
Anaemia (1,231)
Thrombocytopenia (1,214)
What Other Drugs Cause Sepsis?
RITUXIMAB (4,043)
CYCLOPHOSPHAMIDE (4,041)
METHOTREXATE (3,933)
ADALIMUMAB (3,169)
DEXAMETHASONE (3,150)
LENALIDOMIDE (2,956)
VINCRISTINE (2,791)
DOXORUBICIN (2,740)
PREDNISONE (2,634)
PREDNISOLONE (2,281)
Which IRINOTECAN Alternatives Have Lower Sepsis Risk?
IRINOTECAN vs IRON
IRINOTECAN vs IRON DEXTRAN
IRINOTECAN vs IRON ISOMALTOSIDE 1000
IRINOTECAN vs IRON POLYMALTOSE
IRINOTECAN vs IRON SUCROSE