Does ISOFLURANE Cause Metabolic acidosis? 54 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 54 reports of Metabolic acidosis have been filed in association with ISOFLURANE (Isoflurane). This represents 6.5% of all adverse event reports for ISOFLURANE.
54
Reports of Metabolic acidosis with ISOFLURANE
6.5%
of all ISOFLURANE reports
38
Deaths
39
Hospitalizations
How Dangerous Is Metabolic acidosis From ISOFLURANE?
Of the 54 reports, 38 (70.4%) resulted in death, 39 (72.2%) required hospitalization, and 27 (50.0%) were considered life-threatening.
Is Metabolic acidosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ISOFLURANE. However, 54 reports have been filed with the FAERS database.
What Other Side Effects Does ISOFLURANE Cause?
Drug ineffective (134)
Hypotension (127)
Off label use (90)
Hyperthermia malignant (87)
Intestinal ischaemia (77)
Status epilepticus (75)
Systemic inflammatory response syndrome (63)
Necrosis ischaemic (56)
Post procedural complication (55)
Blood creatine phosphokinase increased (52)
What Other Drugs Cause Metabolic acidosis?
METFORMIN (5,236)
ACETAMINOPHEN (2,538)
AMLODIPINE (1,202)
IBUPROFEN (974)
EMPAGLIFLOZIN (572)
TACROLIMUS (491)
VENLAFAXINE (460)
FLUOXETINE (437)
ESOMEPRAZOLE (430)
FUROSEMIDE (413)
Which ISOFLURANE Alternatives Have Lower Metabolic acidosis Risk?
ISOFLURANE vs ISONIAZID
ISOFLURANE vs ISONIAZID\PYRAZINAMIDE\RIFAMPIN
ISOFLURANE vs ISONIAZID\PYRIDOXINE\SULFAMETHOXAZOLE\TRIMETHOPRIM
ISOFLURANE vs ISONIAZID\RIFAMPIN
ISOFLURANE vs ISOPROPANOLAMINE