Does ISOFLURANE Cause Off label use? 90 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 90 reports of Off label use have been filed in association with ISOFLURANE (Isoflurane). This represents 10.9% of all adverse event reports for ISOFLURANE.
90
Reports of Off label use with ISOFLURANE
10.9%
of all ISOFLURANE reports
31
Deaths
43
Hospitalizations
How Dangerous Is Off label use From ISOFLURANE?
Of the 90 reports, 31 (34.4%) resulted in death, 43 (47.8%) required hospitalization, and 35 (38.9%) were considered life-threatening.
Is Off label use Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ISOFLURANE. However, 90 reports have been filed with the FAERS database.
What Other Side Effects Does ISOFLURANE Cause?
Drug ineffective (134)
Hypotension (127)
Hyperthermia malignant (87)
Intestinal ischaemia (77)
Status epilepticus (75)
Systemic inflammatory response syndrome (63)
Necrosis ischaemic (56)
Post procedural complication (55)
Metabolic acidosis (54)
Blood creatine phosphokinase increased (52)
What Other Drugs Cause Off label use?
RITUXIMAB (39,751)
INFLIXIMAB (34,801)
DENOSUMAB (34,612)
METHOTREXATE (24,020)
VEDOLIZUMAB (21,017)
ETANERCEPT (20,178)
TOCILIZUMAB (18,256)
PREDNISONE (17,867)
LENALIDOMIDE (17,017)
ADALIMUMAB (16,417)
Which ISOFLURANE Alternatives Have Lower Off label use Risk?
ISOFLURANE vs ISONIAZID
ISOFLURANE vs ISONIAZID\PYRAZINAMIDE\RIFAMPIN
ISOFLURANE vs ISONIAZID\PYRIDOXINE\SULFAMETHOXAZOLE\TRIMETHOPRIM
ISOFLURANE vs ISONIAZID\RIFAMPIN
ISOFLURANE vs ISOPROPANOLAMINE