Does ISONIAZID Cause Hepatic steatosis? 137 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 137 reports of Hepatic steatosis have been filed in association with ISONIAZID (Isoniazid). This represents 1.8% of all adverse event reports for ISONIAZID.
137
Reports of Hepatic steatosis with ISONIAZID
1.8%
of all ISONIAZID reports
2
Deaths
78
Hospitalizations
How Dangerous Is Hepatic steatosis From ISONIAZID?
Of the 137 reports, 2 (1.5%) resulted in death, 78 (56.9%) required hospitalization, and 2 (1.5%) were considered life-threatening.
Is Hepatic steatosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ISONIAZID. However, 137 reports have been filed with the FAERS database.
What Other Side Effects Does ISONIAZID Cause?
Drug-induced liver injury (766)
Drug ineffective (607)
Drug reaction with eosinophilia and systemic symptoms (550)
Pyrexia (517)
Nausea (488)
Paradoxical drug reaction (433)
Off label use (406)
Drug resistance (367)
Hepatotoxicity (349)
Headache (324)
What Other Drugs Cause Hepatic steatosis?
METHOTREXATE (1,400)
ADALIMUMAB (1,058)
ETANERCEPT (620)
TOCILIZUMAB (476)
TOFACITINIB (405)
LEFLUNOMIDE (359)
HYDROXYCHLOROQUINE (358)
ABATACEPT (345)
METFORMIN (343)
INFLIXIMAB (325)
Which ISONIAZID Alternatives Have Lower Hepatic steatosis Risk?
ISONIAZID vs ISONIAZID\PYRAZINAMIDE\RIFAMPIN
ISONIAZID vs ISONIAZID\PYRIDOXINE\SULFAMETHOXAZOLE\TRIMETHOPRIM
ISONIAZID vs ISONIAZID\RIFAMPIN
ISONIAZID vs ISOPROPANOLAMINE
ISONIAZID vs ISOPROPYL ALCOHOL