Hepatic steatosis: Which Medications Cause It? (11,941 Reports Across 679 Drugs)
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Hepatic steatosis has been reported as an adverse event with 679 different drugs in the FDA's FAERS database, with 11,941 total reports. 1,010 of these reports resulted in death.The drugs most commonly associated with Hepatic steatosis are METHOTREXATE, ADALIMUMAB, and ETANERCEPT.
11,941
Total Reports
679
Drugs Involved
1,010
Deaths
4,327
Hospitalizations
52.4 yrs
Average Patient Age
62.0% / 38.0%
Female / Male
Which Drugs Cause Hepatic steatosis Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| METHOTREXATE | 1,400 | 0.6% | 41 | 423 | 25 |
| ADALIMUMAB | 1,058 | 0.2% | 22 | 384 | 17 |
| ETANERCEPT | 620 | 0.2% | 6 | 135 | 4 |
| TOCILIZUMAB | 476 | 0.5% | 11 | 143 | 6 |
| TOFACITINIB | 405 | 0.3% | 6 | 110 | 5 |
| LEFLUNOMIDE | 359 | 0.6% | 0 | 68 | 3 |
| HYDROXYCHLOROQUINE | 358 | 0.5% | 9 | 81 | 9 |
| ABATACEPT | 345 | 0.3% | 2 | 109 | 6 |
| METFORMIN | 343 | 0.4% | 20 | 126 | 22 |
| INFLIXIMAB | 325 | 0.2% | 3 | 104 | 4 |
| SECUKINUMAB | 308 | 0.2% | 9 | 102 | 13 |
| ATORVASTATIN | 301 | 0.4% | 7 | 88 | 9 |
| RITUXIMAB | 287 | 0.2% | 12 | 105 | 5 |
| PREDNISONE | 283 | 0.2% | 10 | 125 | 15 |
| ACETAMINOPHEN | 281 | 0.2% | 79 | 181 | 59 |
| PANTOPRAZOLE | 249 | 0.3% | 5 | 123 | 3 |
| USTEKINUMAB | 234 | 0.3% | 6 | 39 | 1 |
| CYCLOPHOSPHAMIDE | 233 | 0.2% | 26 | 171 | 49 |
| ALENDRONATE | 206 | 0.7% | 0 | 78 | 1 |
| VINCRISTINE | 196 | 0.3% | 23 | 128 | 45 |