Does ISONIAZID Cause Multiple-drug resistance? 61 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 61 reports of Multiple-drug resistance have been filed in association with ISONIAZID (Isoniazid). This represents 0.8% of all adverse event reports for ISONIAZID.
61
Reports of Multiple-drug resistance with ISONIAZID
0.8%
of all ISONIAZID reports
11
Deaths
12
Hospitalizations
How Dangerous Is Multiple-drug resistance From ISONIAZID?
Of the 61 reports, 11 (18.0%) resulted in death, 12 (19.7%) required hospitalization, and 1 (1.6%) were considered life-threatening.
Is Multiple-drug resistance Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ISONIAZID. However, 61 reports have been filed with the FAERS database.
What Other Side Effects Does ISONIAZID Cause?
Drug-induced liver injury (766)
Drug ineffective (607)
Drug reaction with eosinophilia and systemic symptoms (550)
Pyrexia (517)
Nausea (488)
Paradoxical drug reaction (433)
Off label use (406)
Drug resistance (367)
Hepatotoxicity (349)
Headache (324)
What Other Drugs Cause Multiple-drug resistance?
LEVETIRACETAM (1,378)
LACOSAMIDE (739)
VALPROIC ACID (622)
TOPIRAMATE (521)
CLOBAZAM (486)
LAMOTRIGINE (418)
PHENOBARBITAL (406)
PHENYTOIN (337)
CARBAMAZEPINE (299)
PERAMPANEL (258)
Which ISONIAZID Alternatives Have Lower Multiple-drug resistance Risk?
ISONIAZID vs ISONIAZID\PYRAZINAMIDE\RIFAMPIN
ISONIAZID vs ISONIAZID\PYRIDOXINE\SULFAMETHOXAZOLE\TRIMETHOPRIM
ISONIAZID vs ISONIAZID\RIFAMPIN
ISONIAZID vs ISOPROPANOLAMINE
ISONIAZID vs ISOPROPYL ALCOHOL