Multiple-drug resistance: Which Medications Cause It? (2,700 Reports Across 310 Drugs)
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Multiple-drug resistance has been reported as an adverse event with 310 different drugs in the FDA's FAERS database, with 2,700 total reports. 294 of these reports resulted in death.The drugs most commonly associated with Multiple-drug resistance are LEVETIRACETAM, LACOSAMIDE, and VALPROIC ACID.
2,700
Total Reports
310
Drugs Involved
294
Deaths
573
Hospitalizations
34.9 yrs
Average Patient Age
49.2% / 50.8%
Female / Male
Which Drugs Cause Multiple-drug resistance Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| LEVETIRACETAM | 1,378 | 2.2% | 118 | 255 | 99 |
| LACOSAMIDE | 739 | 3.5% | 83 | 155 | 53 |
| VALPROIC ACID | 622 | 3.1% | 82 | 135 | 59 |
| TOPIRAMATE | 521 | 1.8% | 69 | 79 | 52 |
| CLOBAZAM | 486 | 4.6% | 50 | 79 | 34 |
| LAMOTRIGINE | 418 | 0.9% | 33 | 79 | 17 |
| PHENOBARBITAL | 406 | 6.3% | 27 | 67 | 24 |
| PHENYTOIN | 337 | 2.3% | 38 | 85 | 38 |
| CARBAMAZEPINE | 299 | 1.2% | 34 | 46 | 16 |
| PERAMPANEL | 258 | 5.8% | 35 | 42 | 13 |
| OXCARBAZEPINE | 256 | 2.4% | 27 | 37 | 23 |
| CLONAZEPAM | 246 | 0.6% | 10 | 62 | 10 |
| ZONISAMIDE | 238 | 5.0% | 5 | 24 | 17 |
| MIDAZOLAM | 236 | 2.1% | 37 | 78 | 45 |
| LAMIVUDINE | 186 | 1.1% | 0 | 24 | 0 |
| BRIVARACETAM | 185 | 3.0% | 1 | 30 | 11 |
| LORAZEPAM | 150 | 0.5% | 31 | 53 | 30 |
| METHOTREXATE | 142 | 0.1% | 10 | 27 | 5 |
| PROPOFOL | 129 | 0.8% | 34 | 54 | 41 |
| VALPROATE | 129 | 0.8% | 11 | 38 | 18 |